From Breaking Bad to Worse: Exploiting Homologous DNA Repair Deficiency in Cancer
DNA repair deficiencies are common among cancer cells and represent a potential vulnerability that might be exploited by targeting compensatory repair pathways. However, the identification of synthetically lethal combinations of DNA repair defects, although of significant clinical relevance, has bee...
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
American Association for Cancer Research,
2015-04-07T18:34:44Z.
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| Subjects: | |
| Online Access: | Get fulltext |