Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents

A palladium-catalyzed asymmetric arylation of 9-aminofluorene-derived imines using a chiral dialkylbiaryl phosphine as the supporting ligand has been developed. This transformation allows for enantioselective access to a diverse range of α-branched benzylamines.

Bibliographic Details
Main Authors: Zhu, Ye (Contributor), Buchwald, Stephen Leffler (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-04-09T18:29:18Z.
Subjects:
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