Mechanochemical basis of protein degradation by a double-ring AAA+ machine

Molecular machines containing double or single AAA+ rings power energy-dependent protein degradation and other critical cellular processes, including disaggregation and remodeling of macromolecular complexes. How the mechanical activities of double-ring and single-ring AAA+ enzymes differ is unknown...

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Bibliographic Details
Main Authors: Iosefson, Ohad (Contributor), Olivares, Adrian O. (Contributor), Baker, Tania (Contributor), Nager, Andrew Ross (Contributor), Sauer, Robert T (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Sauer, Robert T. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-04-22T18:35:38Z.
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