Rag GTPase-mediated regulation of mTORC1 by nutrients is necessary for neonatal autophagy and survival
The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates organismal growth in response to many environmental cues, including nutrients and growth factors. Cell-based studies showed that mTORC1 senses amino acids through the RagA-D family of GTPases (also known as RRAGA, B, C and D),...
Main Authors: | , , , , , , , , |
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Other Authors: | , , , |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2015-04-23T17:29:37Z.
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Subjects: | |
Online Access: | Get fulltext |