An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors

Current anticancer chemotherapy relies on a limited set of in vitro or indirect prognostic markers of tumor response to available drugs. A more accurate analysis of drug sensitivity would involve studying tumor response in vivo. To this end, we have developed an implantable device that can perform d...

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Bibliographic Details
Main Authors: Jonas, Oliver H. (Contributor), Landry, Heather M. (Contributor), Fuller, Jason E. (Contributor), Cima, Michael J. (Contributor), Santini, John T., Jr (Author), Baselga, Jose (Author), Tepper, Robert I. (Author), Langer, Robert S (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2015-04-24T15:15:37Z.
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