Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain

Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain

Metastases represent the most common brain tumors in adults. Surgical resection alone results in 45% recurrence and is usually accompanied by radiation and chemotherapy. Adequate chemotherapy delivery to the CNS is hindered by the blood-brain barrier. Efforts at delivering chemotherapy locally to gl...

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Bibliographic Details
Main Authors: Upadhyay, Urvashi M. (Author), Tyler, Betty (Author), Patta, Yoda (Contributor), Wicks, Robert (Author), Scott, Alexander (Contributor), Masi, Byron (Contributor), Hwang, Lee (Author), Grossman, Rachel (Author), Brem, Henry (Author), Cima, Michael J. (Contributor), Langer, Robert S (Author), Spencer, Kevin C (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Spencer, Kevin C. (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-05-11T14:05:17Z.
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