Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins

Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins

RNA binding proteins of the conserved CUGBP1, Elav-like factor (CELF) family contribute to heart and skeletal muscle development and are implicated in myotonic dystrophy (DM). To understand their genome-wide functions, we analyzed the transcriptome dynamics following induction of CELF1 or CELF2 in a...

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Main Authors: Giudice, Jimena (Author), Treacy, Daniel J. (Contributor), Saxena, Tanvi (Contributor), Cooper, Thomas A. (Author), Ward, Amanda (Contributor), Cherone, Jennifer Michelle (Contributor), Freese, Peter Dale (Contributor), Wang, Thomas (Author), Lambert, Nicole (Author), Burge, Christopher B (Author), Wang, Eric T (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Wang, Eric Tzy-shi (Contributor), Wang, Thomas T. (Contributor), Lambert, Nicole J. (Contributor), Burge, Christopher B. (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2015-05-22T18:02:05Z.
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