Critical Role of Smad and AP-1 Complexes in TGF-β-Dependent Apoptosis
Transforming growth factor-β1 (TGF-β1) induces not only cell growth inhibition but also apoptosis in hepatocytes, myeloid cells, and epithelial cells. Smad complexes (Smad2-Smad4 and Smad3-Smad4) are identified as key signaling molecules which transmit TGF-β1 signal for growth inhibition from the TG...
Main Authors: | Yamamura, Yasuko (Author), Hua, Xianxin (Author), Bergelson, Svetlana (Author), Lodish, Harvey F (Author) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Lodish, Harvey F. (Contributor) |
Format: | Article |
Language: | English |
Published: |
Hindawi Publishing Corporation,
2015-06-09T13:37:50Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Critical Role of Smad and AP-1 Complexes in TGF-β-Dependent Apoptosis
by: Yasuko Yamamura, et al.
Published: (2001-01-01) -
Smad2-dependent downregulation of miR-30 is required for TGF-β-induced apoptosis in podocytes.
by: Shaolin Shi, et al.
Published: (2013-01-01) -
Non-degradative ubiquitination in Smad-dependent TGF-β signaling
by: Tang Liu-Ya, et al.
Published: (2011-12-01) -
Smad7 in TGF-β Signalling
by: Brodin, Greger
Published: (2002) -
YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts
by: Zhaoping Qin, et al.
Published: (2018-04-01)