A load driver device for engineering modularity in biological networks

A load driver device for engineering modularity in biological networks

The behavior of gene modules in complex synthetic circuits is often unpredictable. After joining modules to create a circuit, downstream elements (such as binding sites for a regulatory protein) apply a load to upstream modules that can negatively affect circuit function. Here we devised a genetic d...

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Bibliographic Details
Main Authors: Mishra, Deepak (Contributor), Lin, Allen (Contributor), Del Vecchio, Domitilla (Contributor), Weiss, Ron (Contributor), Rivera, Phillip M. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Synthetic Biology Center (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-06-15T14:03:38Z.
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