Versatile RNA Interference Nanoplatform for Systemic Delivery of RNAs

Versatile RNA Interference Nanoplatform for Systemic Delivery of RNAs

Development of nontoxic, tumor-targetable, and potent in vivo RNA delivery systems remains an arduous challenge for clinical application of RNAi therapeutics. Herein, we report a versatile RNAi nanoplatform based on tumor-targeted and pH-responsive nanoformulas (NFs). The NF was engineered by combin...

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Bibliographic Details
Main Authors: Choi, Ki Young (Contributor), Silvestre, Oscar F. (Author), Huang, Xinglu (Author), Min, Kyung Hyun (Author), Howard, Gregory P. (Author), Hida, Naoki (Author), Jin, Albert J. (Contributor), Carvajal, Nicole (Author), Lee, Sang Wook (Author), Hong, Jong-In (Author), Chen, Xiaoyuan (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-06-19T18:44:03Z.
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