Microfluidic Platform for Combinatorial Synthesis and Optimization of Targeted Nanoparticles for Cancer Therapy

Taking a nanoparticle (NP) from discovery to clinical translation has been slow compared to small molecules, in part by the lack of systems that enable their precise engineering and rapid optimization. In this work we have developed a microfluidic platform for the rapid, combinatorial synthesis and...

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Bibliographic Details
Main Authors: Valencia, Pedro M. (Contributor), Pridgen, Eric M. (Contributor), Rhee, Minsoung (Contributor), Langer, Robert (Contributor), Farokhzad, Omid C. (Contributor), Karnik, Rohit (Contributor)
Other Authors: MIT-Harvard Center for Cancer Nanotechnology Excellence (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-06-26T14:54:34Z.
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