Ligation-anchored PCR unveils immune repertoire of TCR-beta from whole blood
Background As one of the genetic mechanisms for adaptive immunity, V(D)J recombination generates an enormous repertoire of T-cell receptors (TCRs). With the development of high-throughput sequencing techniques, systematic exploration of V(D)J recombination becomes possible. Multiplex PCR has been pr...
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| Format: | Article |
| Language: | English |
| Published: |
BioMed Central,
2015-06-29T16:49:55Z.
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| Online Access: | Get fulltext |