Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep

Optogenetic activation of cholinergic neurons in the PPT or LDT induces REM sleep

Rapid eye movement (REM) sleep is an important component of the natural sleep/wake cycle, yet the mechanisms that regulate REM sleep remain incompletely understood. Cholinergic neurons in the mesopontine tegmentum have been implicated in REM sleep regulation, but lesions of this area have had varyin...

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Main Authors: Zheng, Shu (Contributor), Goldblum, Rebecca R. (Contributor), Gelwan, Noah A. (Contributor), Ramos, Daniel M. (Contributor), Nolan, Michael A. (Contributor), Wang, Karen (Contributor), Weng, Feng-Ju (Contributor), Lin, Yingxi (Contributor), Wilson, Matthew A. (Contributor), Brown, Emery N. (Contributor), Van Dort, Christa (Contributor), Zachs, Daniel (Contributor), Kenny, Jonathan Dillion (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Harvard University- (Contributor), Lincoln Laboratory (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-08-05T13:17:21Z.
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