Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates

Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates

Since its discovery and isolation, exogenous insulin has dramatically changed the outlook for patients with diabetes. However, even when patients strictly follow an insulin regimen, serious complications can result as patients experience both hyperglycemic and hypoglycemic states. Several chemically...

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Main Authors: Chou, Danny Hung-Chieh (Contributor), Tang, Benjamin C. (Contributor), Lin, Amy B. (Contributor), Thapa, Lavanya S. (Contributor), Deng, David (Contributor), Truong, Jonathan V. (Contributor), Webber, Matthew (Contributor), Cortinas, Abel Bryan (Contributor), Anderson, Daniel Griffith (Contributor), Langer, Robert S (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-08-05T14:41:44Z.
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