SIRT1-FOXO3a Regulate Cocaine Actions in the Nucleus Accumbens

SIRT1-FOXO3a Regulate Cocaine Actions in the Nucleus Accumbens

Previous studies have shown that chronic cocaine administration induces SIRT1, a Class III histone deacetylase, in the nucleus accumbens (NAc), a key brain reward region, and that such induction influences the gene regulation and place conditioning effects of cocaine. To determine the mechanisms by...

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Main Authors: Ferguson, Deveroux (Author), Shao, Ningyi (Author), Heller, Elizabeth (Author), Feng, Jian (Author), Neve, Rachael L. (Contributor), Kim, Hee-Dae (Author), Call, Tanessa (Author), Magazu, Samantha (Author), Shen, Li (Author), Nestler, Eric J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor)
Format: Article
Language:English
Published: Society for Neuroscience, 2015-08-05T15:26:44Z.
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