Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation

A key aspect of cancer metastases is the tendency for specific cancer cells to home to defined subsets of secondary organs. Despite these known tendencies, the underlying mechanisms remain poorly understood. Here we develop a microfluidic 3D in vitro model to analyze organ-specific human breast canc...

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Bibliographic Details
Main Authors: Jeon, Jessie S. (Contributor), Bersini, Simone (Author), Gilardi, Mara (Author), Dubini, Gabriele (Author), Charest, Joseph L. (Author), Moretti, Matteo (Author), Kamm, Roger Dale (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-08-05T16:14:35Z.
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