Alternative Splicing of Endothelial Fibronectin Is Induced by Disturbed Hemodynamics and Protects Against Hemorrhage of the Vessel Wall
Objective-Abnormally low-flow conditions, sensed by the arterial endothelium, promote aneurysm rupture. Fibronectin (FN) is among the most abundant extracellular matrix proteins and is strongly upregulated in human aneurysms, suggesting a possible role in disease progression. Altered FN splicing can...
| Main Authors: | , |
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| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Ovid Technologies (Wolters Kluwer) -American Heart Association,
2015-08-19T12:01:26Z.
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| Subjects: | |
| Online Access: | Get fulltext |