Kinetics of sickle cell biorheology and implications for painful vasoocclusive crisis

We developed a microfluidics-based model to quantify cell-level processes modulating the pathophysiology of sickle cell disease (SCD). This in vitro model enabled quantitative investigations of the kinetics of cell sickling, unsickling, and cell rheology. We created short-term and long-term hypoxic...

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Bibliographic Details
Main Authors: Du, E (Contributor), Diez-Silva, Monica (Contributor), Kato, Gregory J. (Author), Dao, Ming (Contributor), Suresh, Subra (Author)
Other Authors: Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-09-08T15:27:51Z.
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