In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex

In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex

A wide variety of prokaryotes possess DNA modifications consisting of sequence-specific phosphorothioates (PT) inserted by members of a five-gene cluster. Recent genome mapping studies revealed two unusual features of PT modifications: short consensus sequences and partial modification of a specific...

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Main Authors: Cao, Bo (Contributor), Zheng, Xiaoqing (Author), Cheng, Qiuxiang (Author), Yao, Fen (Author), Zheng, Tao (Author), Ramesh Babu, I. (Contributor), Zhou, Huchen (Author), You, Delin (Author), Dedon, Peter C. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-09-10T13:22:14Z.
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