Development of a fluorogenic sensor for activated Cdc42
Cdc42, a member of the Rho GTPase family, is a fundamental regulator of the actin cytoskeleton during cell migration. To generate a sensor for Cdc42 activation, we employed a multi-pronged approach, utilizing cysteine labeling and expressed protein ligation, to incorporate the environment sensitive...
Main Authors: | , , |
---|---|
Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2015-10-02T17:03:51Z.
|
Subjects: | |
Online Access: | Get fulltext |