Development of a fluorogenic sensor for activated Cdc42
Cdc42, a member of the Rho GTPase family, is a fundamental regulator of the actin cytoskeleton during cell migration. To generate a sensor for Cdc42 activation, we employed a multi-pronged approach, utilizing cysteine labeling and expressed protein ligation, to incorporate the environment sensitive...
Main Authors: | Goguen, Brenda N. (Contributor), Loving, Galen S. (Contributor), Imperiali, Barbara (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2015-10-02T17:03:51Z.
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Subjects: | |
Online Access: | Get fulltext |
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