CD8α[superscript +] Dendritic Cells Are the Critical Source of Interleukin-12 that Controls Acute Infection by Toxoplasma gondii Tachyzoites

CD8α[superscript +] Dendritic Cells Are the Critical Source of Interleukin-12 that Controls Acute Infection by Toxoplasma gondii Tachyzoites

CD8α[superscript +] dendritic cells (DCs) are important in vivo for cross-presentation of antigens derived from intracellular pathogens and tumors. Additionally, secretion of interleukin-12 (IL-12) by CD8α[superscript +] DCs suggests a role for these cells in response to Toxoplasma gondii antigens,...

Full description

Bibliographic Details
Main Authors: Mashayekhi, Mona (Author), Sandau, Michelle M (Author), Dunay, Ildiko R (Author), Frickel, Eva M (Author), Khan, Asis (Author), Goldszmid, Romina S (Author), Sher, Alan (Author), Murphy, Theresa L (Author), Sibley, L. David (Author), Murphy, Kenneth M (Author), Ploegh, Hidde (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Elsevier/Cell Press, 2015-10-06T18:52:06Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items