Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture

Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture

Human embryonic stem cells (hESCs) hold great potential as a resource for regenerative medicine. Before achieving therapeutic relevancy, methods must be developed to control stem cell differentiation. It is clear that stem cells can respond to genetic signals, such as those imparted by nucleic acids...

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Main Authors: Lytton-Jean, Abigail K. R. (Contributor), Deiorio-Haggar, Kaila (Contributor), Bellan, Leon M. (Contributor), Karagiannis, Emmanouil (Contributor), Anderson, Daniel Griffith (Contributor), Zoldan, Janeta (Author), Langer, Robert S (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Media Laboratory (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Zoldan, Janet (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-10-07T15:33:57Z.
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