Covalent Modification of Synthetic Hydrogels with Bioactive Proteins via Sortase-Mediated Ligation

Covalent Modification of Synthetic Hydrogels with Bioactive Proteins via Sortase-Mediated Ligation

Synthetic extracellular matrices are widely used in regenerative medicine and as tools in building in vitro physiological culture models. Synthetic hydrogels display advantageous physical properties, but are challenging to modify with large peptides or proteins. Here, a facile, mild enzymatic postgr...

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Bibliographic Details
Main Authors: Cambria, Elena (Contributor), Kroll, Carsten (Contributor), Krueger, Andrew T. (Contributor), Imperiali, Barbara (Contributor), Chopko Ahrens, Caroline (Contributor), Cook, Christi Dionne (Contributor), Renggli-Frey, Kasper (Author), Griffith, Linda G (Author)
Other Authors: Massachusetts Institute of Technology. Center for Gynepathology Research (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Renggli, Kasper (Contributor), Griffith, Linda G. (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2015-10-22T14:04:02Z.
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