Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α

Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α

Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine that can elicit distinct cellular behaviors under different molecular contexts. Mitogen activated protein kinase (MAPK) pathways, especially the extracellular signal-regulated kinase (Erk) pathway, help to integrate influences from the...

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Bibliographic Details
Main Authors: Lau, Ken S. (Contributor), Gierut, Jessica (Author), Lauffenburger, Douglas A. (Contributor), Haigis, Kevin M. (Author), Schrier, Sarah (Contributor), Lyons, Jesse Stolberg (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2015-10-27T18:09:07Z.
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