A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects

A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects

We describe a rapid method to accurately measure the cytotoxicity of mammalian cells upon exposure to various drugs. Using this assay, we obtain survival data in a fraction of the time required to perform the traditional clonogenic survival assay, considered the gold standard. The dynamic range of t...

Full description

Bibliographic Details
Main Authors: Valiathan, Chandni (Contributor), McFaline, Jose Luis (Contributor), Samson, Leona D. (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-10-29T17:12:29Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items