Genomic mining of prokaryotic repressors for orthogonal logic gates

Genomic mining of prokaryotic repressors for orthogonal logic gates

Genetic circuits perform computational operations based on interactions between freely diffusing molecules within a cell. When transcription factors are combined to build a circuit, unintended interactions can disrupt its function. Here, we apply 'part mining' to build a library of 73 TetR...

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Main Authors: Tamsir, Alvin (Author), Clancy, Kevin (Author), Peterson, Todd (Author), Stanton, Brynne C. (Contributor), Nielsen, Alec Andrew (Contributor), Voigt, Christopher A. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Synthetic Biology Center (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-10-30T15:51:51Z.
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