Periodic retinoic acid-STRA8 signaling intersects with periodic germ-cell competencies to regulate spermatogenesis

Periodic retinoic acid-STRA8 signaling intersects with periodic germ-cell competencies to regulate spermatogenesis

Mammalian spermatogenesis-the transformation of stem cells into millions of haploid spermatozoa-is elaborately organized in time and space. We explored the underlying regulatory mechanisms by genetically and chemically perturbing spermatogenesis in vivo, focusing on spermatogonial differentiation, w...

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Bibliographic Details
Main Authors: Endo, Tsutomu (Author), Romer, Katherine A. (Contributor), Anderson, Ericka L. (Contributor), Baltus, Andrew E. (Contributor), de Rooij, Dirk G. (Author), Page, David C (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Page, David C. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2015-11-02T18:32:22Z.
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