Contact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and β2 integrin interactions

Contact-dependent carcinoma aggregate dispersion by M2a macrophages via ICAM-1 and β2 integrin interactions

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Tumor-associated macrophages (TAMs) can constitute up to 50% of the tumor mass and have strong implications in tumor progression and metastasis. Macrophages are plastic and can polarize to various subtypes that differ in terms of surface receptor expression as well as cytokine and chemokine producti...

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Main Authors: Bai, Jing (Contributor), Adriani, Giulia (Author), Dang, Truong-Minh (Author), Tu, Ting-Yuan (Author), Penny, Hwei-Xian Leong (Author), Wong, Siew-Cheng (Author), Thiery, Jean-Paul (Author), Kamm, Roger Dale (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Impact Journals/National Center for Biotechnology Information (U.S.), 2015-11-04T13:19:50Z.
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