ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets
X chromosome inactivation (XCI) depends on the long noncoding RNA Xist and its recruitment of Polycomb Repressive Complex 2 (PRC2). PRC2 is also targeted to other sites throughout the genome to effect transcriptional repression. Using XCI as a model, we apply an unbiased proteomics approach to isola...
Main Authors: | , , , , , , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2015-11-20T13:57:33Z.
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Subjects: | |
Online Access: | Get fulltext |