An Adaptive Bayesian Approach to Bernoulli-Response Clinical Trials

Traditional clinical trials have been inefficient in their methods of dose finding and dose allocation. In this paper a four-parameter logistic equation is used to model the outcome of Bernoulli-response clinical trials. A Bayesian adaptive design is used to fit the logistic equation to the dose-res...

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Bibliographic Details
Main Author: Stacey, Andrew W.
Format: Others
Published: BYU ScholarsArchive 2007
Subjects:
Online Access:https://scholarsarchive.byu.edu/etd/1446
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=2445&context=etd