An Adaptive Bayesian Approach to Bernoulli-Response Clinical Trials
Traditional clinical trials have been inefficient in their methods of dose finding and dose allocation. In this paper a four-parameter logistic equation is used to model the outcome of Bernoulli-response clinical trials. A Bayesian adaptive design is used to fit the logistic equation to the dose-res...
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Format: | Others |
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BYU ScholarsArchive
2007
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Online Access: | https://scholarsarchive.byu.edu/etd/1446 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=2445&context=etd |