Ribosomal RNA Mutations that Inhibit the Activity of Transfer-Messenger RNA of Stalled Ribosomes
In eubacteria, stalled ribosomes are rescued by a conserved quality-control mechanism involving transfer-messenger RNA (tmRNA) and its protein partner SmpB. Mimicking a tRNA, tmRNA enters stalled ribosomes, adds Ala to the nascent polypeptide, and serves as a template to encode a short peptide that...
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BYU ScholarsArchive
2010
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Online Access: | https://scholarsarchive.byu.edu/etd/2060 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=3059&context=etd |