Chronic AMP-Activated Protein Kinase Activation and a High-Fat Diet Have an Additive Effect on Mitochondria in Rat Skeletal Muscle

Chronic AMP-Activated Protein Kinase Activation and a High-Fat Diet Have an Additive Effect on Mitochondria in Rat Skeletal Muscle

Factors that stimulate mitochondrial biogenesis in skeletal muscle include AMPK, calcium, and circulating FFAs. Chronic treatment with either AICAR, a chemical activator of AMPK, or increasing circulating FFAs with a high fat diet increases mitochondria in rat skeletal muscle. The purpose of this st...

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Bibliographic Details
Main Author: Fillmore, Natasha
Format: Others
Published: BYU ScholarsArchive 2010
Subjects:
AICAR
fiber type
mitochondrial biogenesis
PGC-α
PPARδ
Cell and Developmental Biology
Physiology
Online Access:https://scholarsarchive.byu.edu/etd/2548
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=3547&context=etd

Internet

https://scholarsarchive.byu.edu/etd/2548
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=3547&context=etd

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