XPRIME-EM: Eliciting Expert Prior Information for Motif Exploration Using the Expectation-Maximization Algorithm
Understanding the possible mechanisms of gene transcription regulation is a primary challenge for current molecular biologists. Identifying transcription factor binding sites (TFBSs), also called DNA motifs, is an important step in understanding these mechanisms. Furthermore, many human diseases are...
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BYU ScholarsArchive
2012
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Online Access: | https://scholarsarchive.byu.edu/etd/3589 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=4588&context=etd |