XPRIME-EM: Eliciting Expert Prior Information for Motif Exploration Using the Expectation-Maximization Algorithm
Understanding the possible mechanisms of gene transcription regulation is a primary challenge for current molecular biologists. Identifying transcription factor binding sites (TFBSs), also called DNA motifs, is an important step in understanding these mechanisms. Furthermore, many human diseases are...
Main Author: | Zhou, Wei |
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Format: | Others |
Published: |
BYU ScholarsArchive
2012
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Subjects: | |
Online Access: | https://scholarsarchive.byu.edu/etd/3589 https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=4588&context=etd |
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