Synthesis and Biological Evaluation of Small Molecule Inhibitors of BMPR1b

Methods for preparing an array of potential small molecule inhibitors of Bone Morphogenetic Protein Receptor 1b (BMPR1b) are described. Target molecules were prepared from two general classes: (1) N9-aryl-N6-ureidoadenines, and (2) dicarbamyl iodoacetamides. Recent data from the Peterson lab indi...

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Bibliographic Details
Main Author: Machicao Tello, Paulo Andre
Format: Others
Published: BYU ScholarsArchive 2016
Subjects:
Online Access:https://scholarsarchive.byu.edu/etd/6021
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7020&context=etd