Functional and Mechanistic Insight into the Role of ATG9A in Autophagy

The bulk degradative process of macroautophagy requires the dynamic growth of autophagosomes, which carry cellular contents to the lysosome for recycling. Atg9A, a multi-pass transmembrane protein, is an apical regulator of autophagosome growth, yet its regulatory mechanism remains unclear. Our work...

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Bibliographic Details
Main Author: Weerasekara, Vajira Kaushalya
Format: Others
Published: BYU ScholarsArchive 2017
Subjects:
Online Access:https://scholarsarchive.byu.edu/etd/6644
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7644&context=etd