Characterization of Neuronal Nicotinic Acetylcholine Receptors and their Positive Allosteric Modulators

Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are necessary in memory and cognition. They are pentameric and consist of α and β subunits. They are most commonly heteromeric but, can sometimes be homomeric. nAChRs are activated by many ligands including nico...

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Bibliographic Details
Main Author: Jackson, Doris Clark
Format: Others
Published: BYU ScholarsArchive 2017
Subjects:
Online Access:https://scholarsarchive.byu.edu/etd/6856
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=7856&context=etd