Influence de la structure 3D du site catalytique de la protéine PBP5 dEnterococcus faecium sur son affinité vis-à-vis des β-lactamines
Summary : Enterococcus faecium possesses a low affinity PBP5 that, like in other enterococci, is an important factor contributing to the intrinsic resistance to penicillin. The structure of PBP5 soluble form in complex with benzylpenicillin has been solved at 2.1 Å resolution. On the basis of this 3...
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Universite de Liege
2010
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Online Access: | http://bictel.ulg.ac.be/ETD-db/collection/available/ULgetd-06112010-085558/ |