Influence de la structure 3D du site catalytique de la protéine PBP5 dEnterococcus faecium sur son affinité vis-à-vis des β-lactamines

Summary : Enterococcus faecium possesses a low affinity PBP5 that, like in other enterococci, is an important factor contributing to the intrinsic resistance to penicillin. The structure of PBP5 soluble form in complex with benzylpenicillin has been solved at 2.1 Å resolution. On the basis of this 3...

Full description

Bibliographic Details
Main Author: Henry, Xavier
Other Authors: Piette, Jacques
Format: Others
Published: Universite de Liege 2010
Subjects:
Online Access:http://bictel.ulg.ac.be/ETD-db/collection/available/ULgetd-06112010-085558/