Design, synthesis and biological evaluation of novel coumarinic derivatives as potential anticancer drugs Conception, synthèse et évaluation biologique de dérivés coumariniques en tant qu'agents anticancéreux potentiels

3-bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate (IK9) was recently reported to be a potent inhibitor of cancer cell invasion and angiogenesis. It markedly reduced in vitro invasion of human HT1080 fibrosarcoma cells through collagen-coated porous membranes (Boyden chamber assay) an...

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Bibliographic Details
Main Author: Hemmer, Marc
Other Authors: PIROTTE, Bernard
Format: Others
Published: Universite de Liege 2010
Subjects:
Online Access:http://bictel.ulg.ac.be/ETD-db/collection/available/ULgetd-11152010-182336/

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