The function of yeast frataxin in iron-sulfur cluster biogenesis : a systematic mutagenesis of solvent-exposed side chains of the beta-sheet platform
Friedreich's ataxia is a neurodegenerative disorder caused by the low expression of a mitochondrial protein called frataxin. Studies in the yeast Saccharomyces cerevisiae have unraveled a role for the frataxin homologue (Yfh1p) in iron-sulfur cluster (Fe/S) biosynthesis, probably by interacting...
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| Format: | Others |
| Language: | en |
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Universite catholique de Louvain
2008
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| Online Access: | http://edoc.bib.ucl.ac.be:81/ETD-db/collection/available/BelnUcetd-09052008-122232/ |