Peroxiredoxin expression in the endocrine pancreas and their regulation by pro-inflammatory cytokines

Pro-inflammatory cytokines released from immune cells infiltrating the endocrine pancreas in Type 1 Diabetes (T1D) induce the generation of reactive oxygen and nitrogen species (ROS/RNS). Cytokines are in part cytotoxic to ƓÒ-cells via the production of peroxynitrite (ONOO-). ƓÒ-cell are weakly prot...

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Bibliographic Details
Main Author: Romanus, Pierre
Format: Others
Language:fr
Published: Universite catholique de Louvain 2008
Subjects:
Online Access:http://edoc.bib.ucl.ac.be:81/ETD-db/collection/available/BelnUcetd-11242008-164355/