ALTERATIONS OF MITOCHONDRIAL BIOGENESIS AND ALTERATIONS OF MITOCHONDRIAL ANTIOXIDANT DEFENSE IN FRIEDREICH’S ATAXIA

ALTERATIONS OF MITOCHONDRIAL BIOGENESIS AND ALTERATIONS OF MITOCHONDRIAL ANTIOXIDANT DEFENSE IN FRIEDREICH’S ATAXIA

Friedreich’s ataxia (FRDA) is an autosomal recessive inherited disorder affecting approximately 1 every 40,000 individuals in Western Europe, is characterized by progressive gait and limb ataxia, dysarthria, areflexia, loss of vibratory and position sense, and a progressive weakness of central origi...

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Bibliographic Details
Main Author: Marmolino, Daniele
Other Authors: Decio Eizirik
Format: Others
Language:en
Published: Universite Libre de Bruxelles 2011
Subjects:
mitochondria
ROS
PPARs
frataxin
Friedreich'a ataxia
Online Access:http://theses.ulb.ac.be/ETD-db/collection/available/ULBetd-01262011-142822/

Internet

http://theses.ulb.ac.be/ETD-db/collection/available/ULBetd-01262011-142822/

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