Study of the scaffold properties of the phosphatidylinositol 5-phosphatase SHIP2 by characterization of two binding partners JIP1 and Intersectin1.
SH2-containing inositol polyphosphate 5-phosphatases, SHIP2, has been established as a regulator of the insulin cascade, of cell adhesion and spreading, actin structures, remodelling and cytoskeletal organization. However, the molecular mechanisms underlying these processes still needed additional i...
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| Format: | Others |
| Language: | en |
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Universite Libre de Bruxelles
2009
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| Online Access: | http://theses.ulb.ac.be/ETD-db/collection/available/ULBetd-06082009-113309/ |