Biochemical study of lipid phosphatase SHIP2 in control of PtdIns(3,4,5)P3 in response to serum and H2O2
The control of phosphatidylinositol 3, 4, 5-trisphosphate [PtdIns(3,4,5)P3] level depends on the activities of both PI kinase and PtdIns(3,4,5)P3 phosphatases: 5-phosphatase like SHIP1 and SHIP2, and 3-phosphatase like PTEN. The ubiquitous SH2 domain containing inositol 5-phosphatase SHIP2 contains...
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| Format: | Others |
| Language: | en |
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Universite Libre de Bruxelles
2007
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| Online Access: | http://theses.ulb.ac.be/ETD-db/collection/available/ULBetd-12102007-132337/ |