A Novel in vitro PDE7 Inhibitor Inhibits IL-2 Gene Expression in Activated T Cells and Induces Apoptosis in a B-cell Line and Monocytic Cell Line
Thesis advisor: Thomas C. Chiles === Elevating intracellular cAMP levels can result in a wide range of anti-inflammatory effects and growth arrest and apoptosis in cancer cells, marking phosphodiesterases (PDEs) as potential targets for inflammatory diseases and cancer treatment. PDE7A is proposed t...
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| Format: | Others |
| Language: | English |
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Boston College
2013
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| Online Access: | http://hdl.handle.net/2345/3935 |