Novel Therapies and Biochemical Insights for the GM1 and GM2 Gangliosidoses

Thesis advisor: Thomas N. Seyfried === Gangliosides are glycosphingolipids (GSLs) containing sialic acids that play numerous roles in neuronal maturation, apoptotic signaling, angiogenesis, and cell surface receptor activity. The GM1 and GM2 gangliosidoses are a series of autosomal recessive lysosom...

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Bibliographic Details
Main Author: Arthur, Julian
Format: Others
Language:English
Published: Boston College 2011
Subjects:
Online Access:http://hdl.handle.net/2345/3855