New Insights into Catalysis and Regulation of the Allosteric Enzyme Aspartate Transcarbamoylase

Thesis advisor: Evan R. Kantrowitz === The enzyme aspartate transcarbamoylase (ATCase) is an enzyme in the pyrimidine nucleotide biosynthetic pathway. It was once an attractive target for anti-proliferation drugs but has since become a teaching model due to kinetic properties such as cooperativity a...

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Bibliographic Details
Main Author: Cockrell, Gregory Mercer
Format: Others
Language:English
Published: Boston College 2013
Subjects:
Online Access:http://hdl.handle.net/2345/3156