Tumor subclone structure reconstruction with genomic variation data
Thesis advisor: Gabor Marth === Unlike normal tissue cells, which contain identical copies of the same genome, tumors are composed of genetically divergent cell subpopulations, or subclones. The abilities to identify the number of subclones, their frequencies within the tumor mass, and the evolution...
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| Format: | Others |
| Language: | English |
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Boston College
2014
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| Online Access: | http://hdl.handle.net/2345/bc-ir:104182 |